| Primary information |
|---|
| PRRID | PRRID_0063 |
| Ligand Name | F4 fimbriae |
| Source | Enterotoxigenic Escherichia coli (F4+ ETEC) |
| Sequence of ligand | ADWGPCRTASGDPFIFVTSFTKNIQNPTDNVTGQTYPDFYQWALGDKYSGVCECPSPNPTEARPTLYKTESTLAAGHNSTYFKITNNLEVSTRVYIANVGNVQVPFINKSNSQPGRECDQPTFGWTTGSKGQLSLYIAKPFVGEQNIPQTIIVSVFGTKKENVYSSVPISQVLLSGKVTVTQGCELAAGTSLDIDFGEYQAHDFKGRTGQPPQNVQKIQKELTFNCTNISDGVHIYLSLEGTPNAAYPSAISLGNADVGAVIEDGKGNILKPNDSNSLLEMNPGSLYEYVKRKVTTTITAYPVSTTGKLPAAGDYSGVATMHVELDGGGGGGGGGGATTDLGAKGTLKFSLKISQGHHHHHH |
| Length | 364 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | The binding of ligand to TLR5 ETEC induce IL-6 and IL-8 cytokine secretion by intestinal cells |
| Name of receptor | TLR5 |
| Type of receptor | TLR |
| Source | Porcine |
| Localization | Intestinal Epithelial Cells |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | C0L925.fasta |
| Swiss prot ID | C0L925 |
| Length Of Receptor | 844 |
| Function | It induces proinflammatory responses in porcine intestinal epithelial cells |
| Assay used | Quantitative bacterial adherence assay |
| PMID | 20600278 |
| Year of Publication | 2010 |
| Pubchem assay | NA |
| Pdb | PRR_0063.pdb |
| 3-D Structure | PRR_0063 (View) or (Download) |