Detailed description page of PRRDB2.0

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PRRID_0056 details
Primary information
PRRIDPRRID_0056
Ligand NameMPLA
SourceSalmonella minnesota R595 (Bacteria)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)NC1C(C(C(OC1O)COC2C(C(C(C(O2)CO)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O)O
LengthNA
TypePAMP
OccurenceSynthetic
Role of LigandNA
Name of receptorTLR4
Type of receptorTLR
Source Dogs
Localizationdendritic cells and macrophages
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorF1PDB9.fasta
Swiss prot IDF1PDB9
Length Of Receptor833
Function1,000-fold less toxic than LPS and can be used as vaccines
Assay usedNA
PMID20713100
Year of Publication2010
Pubchem assayNA
PdbPRR_0056.pdb
3-D StructurePRR_0056 (View) or (Download)