Detailed description page of PRRDB2.0

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PRRID_0050 details
Primary information
PRRIDPRRID_0050
Ligand NamePeptidoglycan (PGN)
SourceBacteria
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)N
LengthNA
TypePeptidoglycan
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorTLR2
Type of receptorTLR
Source Chicken
Localizationsplenocytes
Domaincell surface
Sequence of ReceptorQ9DD78.fasta
Swiss prot IDQ9DD78
Length Of Receptor793
FunctionTLR2 and TLR5 promote cellular activation and the production of cytokines including proinflammatory interleukin (IL)-6, as well as those cytokines that help to initiate and modulate the adaptive immune response, including IL-4, IL-12, and interferon (IFN)-c
Assay usedELISA
PMID24797722
Year of Publication2014
Pubchem assayNA
PdbPRR_0050.pdb
3-D StructurePRR_0050 (View) or (Download)