| Primary information |
|---|
| PRRID | PRRID_0048 |
| Ligand Name | dsDNA |
| Source | Listeria monocytogenes (Bacteria) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | LRRFIP1 bound β-catenin and promoted the activation of β-catenin, which subsequently bound IRF3 which leads to the production of IFN-β |
| Name of receptor | LRRFIP1 |
| Type of receptor | Cytosolic receptor |
| Source | RAW264.7 cells |
| Localization | cytoplasm |
| Domain | NA |
| Sequence of Receptor | Q3UZ39.fasta |
| Swiss prot ID | Q3UZ39 |
| Length Of Receptor | 729 |
| Function | It induce the production of type I interferon is important for pathogen elimination. |
| Assay used | ELISA |
| PMID | 20453844 |
| Year of Publication | 2010 |
| Pubchem assay | NA |
| Pdb | PRR_0048.pdb |
| 3-D Structure | PRR_0048 (View) or (Download) |