Detailed description page of PRRDB2.0

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PRRID_0032 details
Primary information
PRRIDPRRID_0032
Ligand NameCryptococcus neoformans
SourceCryptococcus neoformans(fungi)
Sequence of ligandNA
LengthNA
TypeWhole organism
OccurenceNatural
Role of LigandIt inducs the production of IL-1beta , TNF, IL-12 p40 , IFN- gamma, MIP-2, MIP-1 alpha , MIP-1 beta, RANTES, and IP-10.
Name of receptorSCARF1
Type of receptorScavenger receptor
Source Mice
LocalizationMacropahges
DomainNA
Sequence of ReceptorQ68EF1.fasta
Swiss prot IDQ68EF1
Length Of Receptor474
FunctionMacrophages phagocytose and kill C. neoformans and binding of these fungi to endothelial cells initiates tissue invasion.
Assay usedNA
PMID19237602
Year of Publication2009
Pubchem assayNA
PdbPRR_0032.pdb
3-D StructurePRR_0032 (View) or (Download)