| Primary information |
|---|
| PRRID | PRRID_0026 |
| Ligand Name | Long ds RNA |
| Source | EMCV, poliovirus and coxasackie virus; Rotavirus, dengue virus, WNV, murine hepatitis virus(virus) |
| Sequence of ligand | NA |
| Length | NA |
| Type | PAMP |
| Occurence | Natural |
| Role of Ligand | filament formation mediated receptor tetramerization |
| Name of receptor | MDA5 |
| Type of receptor | RLR |
| Source | Human |
| Localization | Cytoplasm, all mammalian cell types |
| Domain | NA |
| Sequence of Receptor | Q53TB6.fasta |
| Swiss prot ID | Q53TB6 |
| Length Of Receptor | 435 |
| Function | MAVS-TRAF3-TBK1/ IKKe-IRF3. MAVS-FADD/ TRAF6-IKKs-NF-jB |
| Assay used | NA |
| PMID | 28374903 |
| Year of Publication | 2017 |
| Pubchem assay | NA |
| Pdb | PRR_0026.pdb |
| 3-D Structure | PRR_0026 (View) or (Download) |