Primary information |
---|
PRRID | PRRID_0022 |
Ligand Name | Lipopolysaccharide (LPS) |
Source | Escherichia coli serotype 0127:B8 (Bacteria) |
Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
Length | NA |
Type | LPS |
Occurence | Natural |
Role of Ligand | Binding of LPS trigger the NFKB pathway. |
Name of receptor | CD14 |
Type of receptor | PRR |
Source | Wistar Rat |
Localization | Pineal gland (pinealocytes) |
Domain | NA |
Sequence of Receptor | Q63691.fasta |
Swiss prot ID | Q63691 |
Length Of Receptor | 372 |
Function | The pineal gland transduces Gram-negative endotoxin stimulation by producing TNF and inhibiting melatonin synthesis |
Assay used | NA |
PMID | 20586888 |
Year of Publication | 2010 |
Pubchem assay | NA |
Pdb | PRR_0022.pdb |
3-D Structure | PRR_0022 (View) or (Download) |