| Primary information |
|---|
| PRRID | PRRID_0022 |
| Ligand Name | Lipopolysaccharide (LPS) |
| Source | Escherichia coli serotype 0127:B8 (Bacteria) |
| Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
| Length | NA |
| Type | LPS |
| Occurence | Natural |
| Role of Ligand | Binding of LPS trigger the NFKB pathway. |
| Name of receptor | CD14 |
| Type of receptor | PRR |
| Source | Wistar Rat |
| Localization | Pineal gland (pinealocytes) |
| Domain | NA |
| Sequence of Receptor | Q63691.fasta |
| Swiss prot ID | Q63691 |
| Length Of Receptor | 372 |
| Function | The pineal gland transduces Gram-negative endotoxin stimulation by producing TNF and inhibiting melatonin synthesis |
| Assay used | NA |
| PMID | 20586888 |
| Year of Publication | 2010 |
| Pubchem assay | NA |
| Pdb | PRR_0022.pdb |
| 3-D Structure | PRR_0022 (View) or (Download) |