| Primary information |
|---|
| PRRID | PRRID_0007 |
| Ligand Name | mt-DNA |
| Source | All vertebrates(others) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | Cellular injury and necrosis |
| Name of receptor | TLR9 |
| Type of receptor | TLR |
| Source | Human |
| Localization | Granulocytes and monocytes |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NRN6 |
| Length Of Receptor | 154 |
| Function | release of interferon type 1 and TNF-a through the activation of IL-1R-associated kinase 1, 2, and 4 and the phosphorylation of p38 MAPK |
| Assay used | NA |
| PMID | 28049142 |
| Year of Publication | 2017 |
| Pubchem assay | NA |
| Pdb | PRR_0007.pdb |
| 3-D Structure | PRR_0007 (View) or (Download) |