| Primary information |
|---|
| PRRID | PRRID_2637 |
| Ligand Name | sulfoglycolipids |
| Source | Mycobacterium tuberculosis (Bacteria) |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)OC(COC1C(C(C(C(O1)CS(=O)(=O)O)O)O)O)COC(=O)CCCCCCCC=CCC=CCC=CCC |
| Length | NA |
| Type | Pattern-associated molecular patterns (PAMPs) |
| Occurence | Natural |
| Role of Ligand | Tuberculosis |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | NA |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | O60603.fasta |
| Swiss prot ID | O60603 |
| Length Of Receptor | 784 |
| Function | inhibit NF-κB activation and subsequent cytokine production or costimulatory molecule expression by acting as competitive antagonists |
| Assay used | TLR2 Binding assay |
| PMID | 28973928 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_2637 |
| Ligand Name | sulfoglycolipids |
| Source | Mycobacterium tuberculosis (Bacteria) |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)OC(COC1C(C(C(C(O1)CS(=O)(=O)O)O)O)O)COC(=O)CCCCCCCC=CCC=CCC=CCC |
| Length | NA |
| Type | Pattern-associated molecular patterns (PAMPs) |
| Occurence | Natural |
| Role of Ligand | Tuberculosis |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | NA |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | O60603.fasta |
| Swiss prot ID | O60603 |
| Length Of Receptor | 784 |
| Function | inhibit NF-κB activation and subsequent cytokine production or costimulatory molecule expression by acting as competitive antagonists |
| Assay used | TLR2 Binding assay |
| PMID | 28973928 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |