Detailed description page of PRRDB2.0

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PRRID_2615 details
Primary information
PRRIDPRRID_2615
Ligand NameSIN-1
SourceNA
Sequence of ligandNA
LengthNA
TypeReactive oxygen species (ROS)
OccurenceSynthetic
Role of LigandSIN-1 produces cell permeable peroxynitrite anions that can react with lipids, DNA and proteins by direct oxidative reaction or by indirect radical-induced mechanisms
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationRAW-Blue cells
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionNA
Assay usedRT-PCR and Western blot,
PMID29175419
Year of Publication2017
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_2615
Ligand NameSIN-1
SourceNA
Sequence of ligandNA
LengthNA
TypeReactive oxygen species (ROS)
OccurenceSynthetic
Role of LigandSIN-1 produces cell permeable peroxynitrite anions that can react with lipids, DNA and proteins by direct oxidative reaction or by indirect radical-induced mechanisms
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationRAW-Blue cells
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionNA
Assay usedRT-PCR and Western blot,
PMID29175419
Year of Publication2017
Pubchem assayPubchem_assay