| Source | EBOV, MV, SeV, NDV, RSV, flu virus, hantavirus,VSV, RV, HCV, JEV, adenovirus, vaccinia virus, HSV,L. |
| Primary information |
|---|
| PRRID | PRRID_2614 |
| Ligand Name | short dsRNA |
| Source | EBOV, MV, SeV, NDV, RSV, flu virus, hantavirus,VSV, RV, HCV, JEV, adenovirus, vaccinia virus, HSV,L. |
| Sequence of ligand | NA |
| Length | NA |
| Type | Pattern-associated molecular patterns (PAMPs) |
| Occurence | Natural |
| Role of Ligand | K63-polyubiquitination/ polyubiquitin chain binding mediated receptor tetramerization |
| Name of receptor | RIG-1 |
| Type of receptor | Rig-like receptor (RLR) |
| Source | Human |
| Localization | Cytoplasm, all mammalian cell types |
| Domain | NA |
| Sequence of Receptor | O95786.fasta |
| Swiss prot ID | O95786 |
| Length Of Receptor | 925 |
| Function | MAVS-TRAF3-TBK1/ IKKe-IRF3. MAVS-FADD/ TRAF6-IKKs-NF-jB |
| Assay used | NA |
| PMID | 28374903 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |