Detailed description page of PRRDB2.0

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PRRID_2584 details
Primary information
PRRIDPRRID_2584
Ligand Namerb-dsRNA
SourceRice- bran (plant)
Sequence of ligandNA
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of Ligandactivate caspase 1 via TRIF, resulting in the release of IL-1b and LDH
Name of receptorMDA5
Type of receptorRig-like receptor (RLR)
Source Mice
LocalizationNA
DomainNA
Sequence of ReceptorQ8R5F7.fasta
Swiss prot IDQ8R5F7
Length Of Receptor1025
FunctionCaspase 1 activation is specifically induced by TLR3 signaling through TRIF/RIPK/ FADD.
Assay usedRT-qPCR
PMID28848065
Year of Publication2017
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_2584
Ligand Namerb-dsRNA
SourceRice- bran (plant)
Sequence of ligandNA
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of Ligandactivate caspase 1 via TRIF, resulting in the release of IL-1b and LDH
Name of receptorMDA5
Type of receptorRig-like receptor (RLR)
Source Mice
LocalizationNA
DomainNA
Sequence of ReceptorQ8R5F7.fasta
Swiss prot IDQ8R5F7
Length Of Receptor1025
FunctionCaspase 1 activation is specifically induced by TLR3 signaling through TRIF/RIPK/ FADD.
Assay usedRT-qPCR
PMID28848065
Year of Publication2017
Pubchem assayPubchem_assay