Detailed description page of PRRDB2.0

This page displays user query in tabular form.

PRRID_2583 details
Primary information
PRRIDPRRID_2583
Ligand Namerb-dsRNA
SourceRice- bran (plant)
Sequence of ligandNA
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of Ligandactivate caspase 1 via TRIF, resulting in the release of IL-1b and LDH
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ99MB1.fasta
Swiss prot IDQ99MB1
Length Of Receptor905
FunctionCaspase 1 activation is specifically induced by TLR3 signaling through TRIF/RIPK/ FADD, resulting in activation of the NLRP3 inflammasome
Assay usedRT-qPCR
PMID28848065
Year of Publication2017
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_2583
Ligand Namerb-dsRNA
SourceRice- bran (plant)
Sequence of ligandNA
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of Ligandactivate caspase 1 via TRIF, resulting in the release of IL-1b and LDH
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ99MB1.fasta
Swiss prot IDQ99MB1
Length Of Receptor905
FunctionCaspase 1 activation is specifically induced by TLR3 signaling through TRIF/RIPK/ FADD, resulting in activation of the NLRP3 inflammasome
Assay usedRT-qPCR
PMID28848065
Year of Publication2017
Pubchem assayPubchem_assay