Primary information |
---|
PRRID | PRRID_2583 |
Ligand Name | rb-dsRNA |
Source | Rice- bran (plant) |
Sequence of ligand | NA |
Length | NA |
Type | Pattern-associated molecular patterns (PAMPs) |
Occurence | Natural |
Role of Ligand | activate caspase 1 via TRIF, resulting in the release of IL-1b and LDH |
Name of receptor | Toll-like receptor 3 (TLR3) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | NA |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | Q99MB1.fasta |
Swiss prot ID | Q99MB1 |
Length Of Receptor | 905 |
Function | Caspase 1 activation is specifically induced by TLR3 signaling through TRIF/RIPK/ FADD, resulting in activation of the NLRP3 inflammasome |
Assay used | RT-qPCR |
PMID | 28848065 |
Year of Publication | 2017 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_2583 |
Ligand Name | rb-dsRNA |
Source | Rice- bran (plant) |
Sequence of ligand | NA |
Length | NA |
Type | Pattern-associated molecular patterns (PAMPs) |
Occurence | Natural |
Role of Ligand | activate caspase 1 via TRIF, resulting in the release of IL-1b and LDH |
Name of receptor | Toll-like receptor 3 (TLR3) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | NA |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | Q99MB1.fasta |
Swiss prot ID | Q99MB1 |
Length Of Receptor | 905 |
Function | Caspase 1 activation is specifically induced by TLR3 signaling through TRIF/RIPK/ FADD, resulting in activation of the NLRP3 inflammasome |
Assay used | RT-qPCR |
PMID | 28848065 |
Year of Publication | 2017 |
Pubchem assay | Pubchem_assay |