| Primary information |
|---|
| PRRID | PRRID_2583 |
| Ligand Name | rb-dsRNA |
| Source | Rice- bran (plant) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Pattern-associated molecular patterns (PAMPs) |
| Occurence | Natural |
| Role of Ligand | activate caspase 1 via TRIF, resulting in the release of IL-1b and LDH |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | NA |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | Q99MB1.fasta |
| Swiss prot ID | Q99MB1 |
| Length Of Receptor | 905 |
| Function | Caspase 1 activation is specifically induced by TLR3 signaling through TRIF/RIPK/ FADD, resulting in activation of the NLRP3 inflammasome |
| Assay used | RT-qPCR |
| PMID | 28848065 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_2583 |
| Ligand Name | rb-dsRNA |
| Source | Rice- bran (plant) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Pattern-associated molecular patterns (PAMPs) |
| Occurence | Natural |
| Role of Ligand | activate caspase 1 via TRIF, resulting in the release of IL-1b and LDH |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | NA |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | Q99MB1.fasta |
| Swiss prot ID | Q99MB1 |
| Length Of Receptor | 905 |
| Function | Caspase 1 activation is specifically induced by TLR3 signaling through TRIF/RIPK/ FADD, resulting in activation of the NLRP3 inflammasome |
| Assay used | RT-qPCR |
| PMID | 28848065 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |