| Primary information |
|---|
| PRRID | PRRID_2580 |
| Ligand Name | R837 |
| Source | SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus)
|
| Sequence of ligand | NA |
| Length | NA |
| Type | Pattern-associated molecular patterns (PAMPs) |
| Occurence | Natural |
| Role of Ligand | Z-loop proteolytic cleavage, and receptor dimer conformational change |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Endosomes. Innate immune cells except neutrophils and pDCs |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | O15455.fasta |
| Swiss prot ID | O15455 |
| Length Of Receptor | 904 |
| Function | MyD88-IRAK4/ IRAK1-IRF7. MyD88-IRAF6- IKKs-NF-jB |
| Assay used | NA |
| PMID | 28374903 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_2580 |
| Ligand Name | R837 |
| Source | SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus)
|
| Sequence of ligand | NA |
| Length | NA |
| Type | Pattern-associated molecular patterns (PAMPs) |
| Occurence | Natural |
| Role of Ligand | Z-loop proteolytic cleavage, and receptor dimer conformational change |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Endosomes. Innate immune cells except neutrophils and pDCs |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | O15455.fasta |
| Swiss prot ID | O15455 |
| Length Of Receptor | 904 |
| Function | MyD88-IRAK4/ IRAK1-IRF7. MyD88-IRAF6- IKKs-NF-jB |
| Assay used | NA |
| PMID | 28374903 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |