Detailed description page of PRRDB2.0

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PRRID_2570 details
Primary information
PRRIDPRRID_2570
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandImmunostimulant
Name of receptorCcToll-like receptor 22 (TLR22)
Type of receptorToll-like receptor (TLR)
Source Cyprinus carpio L
LocalizationAll tested tissue
DomainA signal peptide, 16 LRR domains, a LRRCT domain in the extracellular region and a TIR domain.
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionactivate NF-κB.
Assay usedRT-qPCR
PMID28192255
Year of Publication2017
Pubchem assayNA
Primary information
PRRIDPRRID_2570
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandImmunostimulant
Name of receptorCcToll-like receptor 22 (TLR22)
Type of receptorToll-like receptor (TLR)
Source Cyprinus carpio L
LocalizationAll tested tissue
DomainA signal peptide, 16 LRR domains, a LRRCT domain in the extracellular region and a TIR domain.
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionactivate NF-κB.
Assay usedRT-qPCR
PMID28192255
Year of Publication2017
Pubchem assayNA