Primary information |
---|
PRRID | PRRID_2529 |
Ligand Name | Palmitic acid |
Source | NA |
Sequence of ligand | CCCCCCCCCCCCCCCC(=O)O |
Length | NA |
Type | Pattern-associated molecular patterns (PAMPs) |
Occurence | Natural |
Role of Ligand | PA may func- tion as a dietary immune modifier (DIM) resulting in the induction of chronic inflammation, such as that seen in type 2 diabetes. |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | Dendritic cell |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | O00206.fasta |
Swiss prot ID | O00206 |
Length Of Receptor | 839 |
Function | production of IL-1β in human DCs through an inflammasome dependent mechanism |
Assay used | qRT-PCR |
PMID | 28463985 |
Year of Publication | 2017 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_2529 |
Ligand Name | Palmitic acid |
Source | NA |
Sequence of ligand | CCCCCCCCCCCCCCCC(=O)O |
Length | NA |
Type | Pattern-associated molecular patterns (PAMPs) |
Occurence | Natural |
Role of Ligand | PA may func- tion as a dietary immune modifier (DIM) resulting in the induction of chronic inflammation, such as that seen in type 2 diabetes. |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | Dendritic cell |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | O00206.fasta |
Swiss prot ID | O00206 |
Length Of Receptor | 839 |
Function | production of IL-1β in human DCs through an inflammasome dependent mechanism |
Assay used | qRT-PCR |
PMID | 28463985 |
Year of Publication | 2017 |
Pubchem assay | Pubchem_assay |