| Primary information |
|---|
| PRRID | PRRID_2529 |
| Ligand Name | Palmitic acid |
| Source | NA |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)O |
| Length | NA |
| Type | Pattern-associated molecular patterns (PAMPs) |
| Occurence | Natural |
| Role of Ligand | PA may func- tion as a dietary immune modifier (DIM) resulting in the induction of chronic inflammation, such as that seen in type 2 diabetes. |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Dendritic cell |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | O00206.fasta |
| Swiss prot ID | O00206 |
| Length Of Receptor | 839 |
| Function | production of IL-1β in human DCs through an inflammasome dependent mechanism |
| Assay used | qRT-PCR |
| PMID | 28463985 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_2529 |
| Ligand Name | Palmitic acid |
| Source | NA |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)O |
| Length | NA |
| Type | Pattern-associated molecular patterns (PAMPs) |
| Occurence | Natural |
| Role of Ligand | PA may func- tion as a dietary immune modifier (DIM) resulting in the induction of chronic inflammation, such as that seen in type 2 diabetes. |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Dendritic cell |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | O00206.fasta |
| Swiss prot ID | O00206 |
| Length Of Receptor | 839 |
| Function | production of IL-1β in human DCs through an inflammasome dependent mechanism |
| Assay used | qRT-PCR |
| PMID | 28463985 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |