| Primary information |
|---|
| PRRID | PRRID_2467 |
| Ligand Name | NA |
| Source | F. solani (fungi) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Pattern-associated molecular patterns (PAMPs) |
| Occurence | Natural |
| Role of Ligand | upregulate AMPs hBD2 and LL37 at the mRNA and protein level via a TLR2- and Dectin-1– mediated mechanism. |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Human corneal epithelial cells (HCECs) |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | O60603.fasta |
| Swiss prot ID | O60603 |
| Length Of Receptor | 784 |
| Function | decreased AMP mRNA upregulation |
| Assay used | RT-PCR, antifungal assay |
| PMID | 28460048 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_2467 |
| Ligand Name | NA |
| Source | F. solani (fungi) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Pattern-associated molecular patterns (PAMPs) |
| Occurence | Natural |
| Role of Ligand | upregulate AMPs hBD2 and LL37 at the mRNA and protein level via a TLR2- and Dectin-1– mediated mechanism. |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Human corneal epithelial cells (HCECs) |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | O60603.fasta |
| Swiss prot ID | O60603 |
| Length Of Receptor | 784 |
| Function | decreased AMP mRNA upregulation |
| Assay used | RT-PCR, antifungal assay |
| PMID | 28460048 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |