Detailed description page of PRRDB2.0
| This page displays user query in tabular form. |
PRRID_2218 details |
| Primary information | |
|---|---|
| PRRID | PRRID_2218 |
| Ligand Name | KIN 1400 |
| Source | NA |
| Sequence of ligand | NA |
| Length | NA |
| Type | hydroxyquinoline |
| Occurence | Synthetic |
| Role of Ligand | able to inhibit replication of a broad spectrum of viruses (Flaviviridae, Filoviridae, Para- myxoviridae, Arenaviridae, and Orthomyxoviridae) to varying degrees by driving IRF3-dependent antiviral gene expression. |
| Name of receptor | RIG-1 |
| Type of receptor | Rig-like receptor (RLR) |
| Source | Human |
| Localization | Cytoplasm |
| Domain | Carbohydrate recognition domain (CRD) |
| Sequence of Receptor | O95786.fasta |
| Swiss prot ID | O95786 |
| Length Of Receptor | 925 |
| Function | NF-κB-mediated in ammatory cytokine pro- duction. |
| Assay used | NA |
| PMID | 28776416 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |
| Primary information | |
|---|---|
| PRRID | PRRID_2218 |
| Ligand Name | KIN 1400 |
| Source | NA |
| Sequence of ligand | NA |
| Length | NA |
| Type | hydroxyquinoline |
| Occurence | Synthetic |
| Role of Ligand | able to inhibit replication of a broad spectrum of viruses (Flaviviridae, Filoviridae, Para- myxoviridae, Arenaviridae, and Orthomyxoviridae) to varying degrees by driving IRF3-dependent antiviral gene expression. |
| Name of receptor | RIG-1 |
| Type of receptor | Rig-like receptor (RLR) |
| Source | Human |
| Localization | Cytoplasm |
| Domain | Carbohydrate recognition domain (CRD) |
| Sequence of Receptor | O95786.fasta |
| Swiss prot ID | O95786 |
| Length Of Receptor | 925 |
| Function | NF-κB-mediated in ammatory cytokine pro- duction. |
| Assay used | NA |
| PMID | 28776416 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |