Detailed description page of PRRDB2.0

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PRRID_2129 details
Primary information
PRRIDPRRID_2129
Ligand NameHeat-shock protein 70
SourceNA
Sequence of ligandMAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD
Length641
TypeDamage-associated molecular patterns (DAMPs)
OccurenceNatural
Role of LigandNA
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationMicroglia
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
Functioninvolved in both amyloid-β uptake and inflammatory cytokine production
Assay usedNA
PMID28801521
Year of Publication2017
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_2129
Ligand NameHeat-shock protein 70
SourceNA
Sequence of ligandMAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPIISGLYQGAGAPGAGGFGAQAPKGASGSGPTIEEVD
Length641
TypeDamage-associated molecular patterns (DAMPs)
OccurenceNatural
Role of LigandNA
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationMicroglia
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
Functioninvolved in both amyloid-β uptake and inflammatory cytokine production
Assay usedNA
PMID28801521
Year of Publication2017
Pubchem assayPubchem_assay