Detailed description page of PRRDB2.0

This page displays user query in tabular form.

PRRID_2094 details
Primary information
PRRIDPRRID_2094
Ligand NameGW4064
SourceNA
Sequence of ligandNA
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandGW4064 attenuated LPS-induced ileum injury and mitochondria dysfunction by sup- pressed TLR4/MyD88 signaling-mediated inflammation and apoptosis.
Name of receptorFarnesoid X receptor (FXR)
Type of receptorPattern recognition receptor (PRR)
Source Mice
LocalizationMacrophages
DomainNA
Sequence of ReceptorQ60641.fasta
Swiss prot IDQ60641
Length Of Receptor488
Functionrole in enteroprotection and mucosal injury by regulating inflammatory responses and barrier function in the intestinal tract.
Assay usedRT-qPCR
PMID28647362
Year of Publication2017
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_2094
Ligand NameGW4064
SourceNA
Sequence of ligandNA
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandGW4064 attenuated LPS-induced ileum injury and mitochondria dysfunction by sup- pressed TLR4/MyD88 signaling-mediated inflammation and apoptosis.
Name of receptorFarnesoid X receptor (FXR)
Type of receptorPattern recognition receptor (PRR)
Source Mice
LocalizationMacrophages
DomainNA
Sequence of ReceptorQ60641.fasta
Swiss prot IDQ60641
Length Of Receptor488
Functionrole in enteroprotection and mucosal injury by regulating inflammatory responses and barrier function in the intestinal tract.
Assay usedRT-qPCR
PMID28647362
Year of Publication2017
Pubchem assayPubchem_assay