Detailed description page of PRRDB2.0

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PRRID_1850 details
Primary information
PRRIDPRRID_1850
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandImmunostimulant
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorO15455.fasta
Swiss prot IDO15455
Length Of Receptor904
FunctionTLR3 (Poly I:C)-mediated, NO-dependent antiviral response [89] in murine embryonic fibroblasts
Assay usedNA
PMID27233799
Year of Publication2016
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1850
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandImmunostimulant
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorO15455.fasta
Swiss prot IDO15455
Length Of Receptor904
FunctionTLR3 (Poly I:C)-mediated, NO-dependent antiviral response [89] in murine embryonic fibroblasts
Assay usedNA
PMID27233799
Year of Publication2016
Pubchem assayPubchem_assay