Detailed description page of PRRDB2.0

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PRRID_1760 details
Primary information
PRRIDPRRID_1760
Ligand Namelipophosphoglycans (LPG)
SourceLeishmania infantum (others)
Sequence of ligandNA
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandCauses visceral and cutaneous leishmaniasis, immunomodulatory
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice (Murine)
LocalizationMacrophages
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
Functionactivate MAPKs and the NF-κB inhibitor p-IκBα,
Assay usedNA
PMID27508930
Year of Publication2016
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1760
Ligand Namelipophosphoglycans (LPG)
SourceLeishmania infantum (others)
Sequence of ligandNA
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandCauses visceral and cutaneous leishmaniasis, immunomodulatory
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice (Murine)
LocalizationMacrophages
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
Functionactivate MAPKs and the NF-κB inhibitor p-IκBα,
Assay usedNA
PMID27508930
Year of Publication2016
Pubchem assayPubchem_assay