Detailed description page of PRRDB2.0

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PRRID_1693 details
Primary information
PRRIDPRRID_1693
Ligand NameCpG-ODN 1826
SourceNA
Sequence of ligand5’-tccatgacgttcctgacgtt-3’
Length20
TypeNucleic Acid
OccurenceSynthetic
Role of LigandTLR9 stimulation induces apoptosis of neurons via SARM1 signalling pathway
Name of receptorToll-like receptor 9 (TLR9)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationPrimary cortical neurons
DomainNA
Sequence of ReceptorQ9NR96.fasta
Swiss prot IDQ9NR96
Length Of Receptor1032
FunctionIt resulted in neuronal apoptosis in primary cortical neuronal cultures and olfactory sensory neurons.
Assay usedMTT assay
PMID26423149
Year of Publication2015
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1693
Ligand NameCpG-ODN 1826
SourceNA
Sequence of ligand5’-tccatgacgttcctgacgtt-3’
Length20
TypeNucleic Acid
OccurenceSynthetic
Role of LigandTLR9 stimulation induces apoptosis of neurons via SARM1 signalling pathway
Name of receptorToll-like receptor 9 (TLR9)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationPrimary cortical neurons
DomainNA
Sequence of ReceptorQ9NR96.fasta
Swiss prot IDQ9NR96
Length Of Receptor1032
FunctionIt resulted in neuronal apoptosis in primary cortical neuronal cultures and olfactory sensory neurons.
Assay usedMTT assay
PMID26423149
Year of Publication2015
Pubchem assayPubchem_assay