Detailed description page of PRRDB2.0
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PRRID_1635 details |
| Primary information | |
|---|---|
| PRRID | PRRID_1635 |
| Ligand Name | single-stranded RNA |
| Source | Virus |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | triggers immune responses |
| Name of receptor | Toll-like receptor 7 (TLR7) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | pDCs |
| Domain | TLR7 signalling via the adaptor MYD88 |
| Sequence of Receptor | Q9NYK1.fasta |
| Swiss prot ID | Q9NYK1 |
| Length Of Receptor | 1049 |
| Function | activation of either nuclear factor-κB (NF-κB) or IFN-regulatory factor 7 (IRF7), which are transcription factors that are responsible for stimulating the expression of pro-inflammatory cytokines and type I IFNs, respectively. |
| Assay used | NA |
| PMID | 24762827 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information | |
|---|---|
| PRRID | PRRID_1635 |
| Ligand Name | single-stranded RNA |
| Source | Virus |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | triggers immune responses |
| Name of receptor | Toll-like receptor 7 (TLR7) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | pDCs |
| Domain | TLR7 signalling via the adaptor MYD88 |
| Sequence of Receptor | Q9NYK1.fasta |
| Swiss prot ID | Q9NYK1 |
| Length Of Receptor | 1049 |
| Function | activation of either nuclear factor-κB (NF-κB) or IFN-regulatory factor 7 (IRF7), which are transcription factors that are responsible for stimulating the expression of pro-inflammatory cytokines and type I IFNs, respectively. |
| Assay used | NA |
| PMID | 24762827 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |