Primary information |
---|
PRRID | PRRID_1608 |
Ligand Name | RNA oligoribonucleotides (ORN) |
Source | Virus |
Sequence of ligand | 5’ -GGACGGAAAGACCCCGUGG- 3’ |
Length | 19 |
Type | Nucleic Acid |
Occurence | Synthetic |
Role of Ligand | elicit innate immune response |
Name of receptor | Toll-like receptor 8 (TLR8) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | monocyte-derived dendritic cells,polymorphonuclear leukocytes (PMN) |
Domain | extracellular domain (ECD) |
Sequence of Receptor | Q9NR97.fasta |
Swiss prot ID | Q9NR97 |
Length Of Receptor | 1041 |
Function | controlling antiviral host defense or autoimmune diseases and TLR8 and respond to its activation with TNF production and/or degranulation |
Assay used | Microarray analysis, Quantitative PCR, Phosphoproteomic screen, Confocal cell imaging,RNA40 pull-down assay and Immunoblot |
PMID | 24813206 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_1608 |
Ligand Name | RNA oligoribonucleotides (ORN) |
Source | Virus |
Sequence of ligand | 5’ -GGACGGAAAGACCCCGUGG- 3’ |
Length | 19 |
Type | Nucleic Acid |
Occurence | Synthetic |
Role of Ligand | elicit innate immune response |
Name of receptor | Toll-like receptor 8 (TLR8) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | monocyte-derived dendritic cells,polymorphonuclear leukocytes (PMN) |
Domain | extracellular domain (ECD) |
Sequence of Receptor | Q9NR97.fasta |
Swiss prot ID | Q9NR97 |
Length Of Receptor | 1041 |
Function | controlling antiviral host defense or autoimmune diseases and TLR8 and respond to its activation with TNF production and/or degranulation |
Assay used | Microarray analysis, Quantitative PCR, Phosphoproteomic screen, Confocal cell imaging,RNA40 pull-down assay and Immunoblot |
PMID | 24813206 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |