| Primary information |
|---|
| PRRID | PRRID_1600 |
| Ligand Name | Recombinant IFNβ |
| Source | CHO cells(others) |
| Sequence of ligand | MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNCQCQKLLWQLNGRLEYCLKDRRNFDIPEEIKQLQQFQKEDAAVTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQRNHLKTVLEEKLEKEDFTRGKRMSSLHLKRYYGRILHYLKAKEDSHCAWTIVRVEILRNFYVINRLTGYLRN |
| Length | 187 |
| Type | Protein |
| Occurence | Synthetic |
| Role of Ligand | play an important role in inducing non-specific resistance against a broad range of viral infections. |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | nasal mucosa Mesenchymal stromal cells (nmMSCs) inferior nasal concha of healthy individuals |
| Domain | endosomal receptor |
| Sequence of Receptor | O15455.fasta |
| Swiss prot ID | O15455 |
| Length Of Receptor | 904 |
| Function | TLR3 ligands induced the release of both proinflammatory cytokines [interleukin (IL)-6 and IL-8] and type I interferon by nmMSCs compared with other TLR ligands |
| Assay used | ELISA and Immunofluoroscence assay |
| PMID | 24830384 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1600 |
| Ligand Name | Recombinant IFNβ |
| Source | CHO cells(others) |
| Sequence of ligand | MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNCQCQKLLWQLNGRLEYCLKDRRNFDIPEEIKQLQQFQKEDAAVTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQRNHLKTVLEEKLEKEDFTRGKRMSSLHLKRYYGRILHYLKAKEDSHCAWTIVRVEILRNFYVINRLTGYLRN |
| Length | 187 |
| Type | Protein |
| Occurence | Synthetic |
| Role of Ligand | play an important role in inducing non-specific resistance against a broad range of viral infections. |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | nasal mucosa Mesenchymal stromal cells (nmMSCs) inferior nasal concha of healthy individuals |
| Domain | endosomal receptor |
| Sequence of Receptor | O15455.fasta |
| Swiss prot ID | O15455 |
| Length Of Receptor | 904 |
| Function | TLR3 ligands induced the release of both proinflammatory cytokines [interleukin (IL)-6 and IL-8] and type I interferon by nmMSCs compared with other TLR ligands |
| Assay used | ELISA and Immunofluoroscence assay |
| PMID | 24830384 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |