Detailed description page of PRRDB2.0

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PRRID_1587 details
Primary information
PRRIDPRRID_1587
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandpoly I:C expressed significantly higher levels of IFN-a1 and IFN-c and Mx
Name of receptorToll-like receptor 22a1 (TLR22a1)
Type of receptorToll-like receptor (TLR)
Source Atlantic salmon (Salmo salar)
Localizationmuscle, head kidney, liver, gut, heart, spleen and gill
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionparalleled TLR3 up-regulation in virus- infected fish
Assay usedReal-time PCR
PMID24736205
Year of Publication2014
Pubchem assayNA
Primary information
PRRIDPRRID_1587
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandpoly I:C expressed significantly higher levels of IFN-a1 and IFN-c and Mx
Name of receptorToll-like receptor 22a1 (TLR22a1)
Type of receptorToll-like receptor (TLR)
Source Atlantic salmon (Salmo salar)
Localizationmuscle, head kidney, liver, gut, heart, spleen and gill
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionparalleled TLR3 up-regulation in virus- infected fish
Assay usedReal-time PCR
PMID24736205
Year of Publication2014
Pubchem assayNA