Detailed description page of PRRDB2.0

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PRRID_1575 details
Primary information
PRRIDPRRID_1575
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandact as a TLR3 agonist and induces protective responses against rapidly growing tumor cells
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationKeratinocytes and mouse skin
Domaincell compartment
Sequence of ReceptorQ99MB1.fasta
Swiss prot IDQ99MB1
Length Of Receptor905
Functionimportant for inflammation in the skin following injury
Assay usedNA
PMID24786223
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1575
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandact as a TLR3 agonist and induces protective responses against rapidly growing tumor cells
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationKeratinocytes and mouse skin
Domaincell compartment
Sequence of ReceptorQ99MB1.fasta
Swiss prot IDQ99MB1
Length Of Receptor905
Functionimportant for inflammation in the skin following injury
Assay usedNA
PMID24786223
Year of Publication2014
Pubchem assayPubchem_assay