Detailed description page of PRRDB2.0

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PRRID_1557 details
Primary information
PRRIDPRRID_1557
Ligand NamePeptidoglycan (PGN)
SourceGram negative Bacteria (Bacteria)
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)N
LengthNA
TypePeptidoglycan
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationmonocyte/macrophages, Myeloid DCs, neutrophils, Mast cells
Domainextracellular domain with leucine-rich repeats and a conservative intracellular Toll/IL- 1 receptor (TIR) domain
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedELISA
PMID24757287
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1557
Ligand NamePeptidoglycan (PGN)
SourceGram negative Bacteria (Bacteria)
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)N
LengthNA
TypePeptidoglycan
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationmonocyte/macrophages, Myeloid DCs, neutrophils, Mast cells
Domainextracellular domain with leucine-rich repeats and a conservative intracellular Toll/IL- 1 receptor (TIR) domain
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedELISA
PMID24757287
Year of Publication2014
Pubchem assayPubchem_assay