| Primary information |
|---|
| PRRID | PRRID_1552 |
| Ligand Name | Peptidoglycan (PGN) |
| Source | Gram-positive bacteria |
| Sequence of ligand | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N |
| Length | NA |
| Type | Peptidoglycan |
| Occurence | Natural |
| Role of Ligand | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 |
| Name of receptor | Toll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells |
| Domain | Cell Surface (Exogenous) |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | fundamental role in pathogen recognition and activation of innate immunity. |
| Assay used | ELISA |
| PMID | 24771328 |
| Year of Publication | 2014 |
| Pubchem assay | NA |
| Primary information |
|---|
| PRRID | PRRID_1552 |
| Ligand Name | Peptidoglycan (PGN) |
| Source | Gram-positive bacteria |
| Sequence of ligand | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N |
| Length | NA |
| Type | Peptidoglycan |
| Occurence | Natural |
| Role of Ligand | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 |
| Name of receptor | Toll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells |
| Domain | Cell Surface (Exogenous) |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | fundamental role in pathogen recognition and activation of innate immunity. |
| Assay used | ELISA |
| PMID | 24771328 |
| Year of Publication | 2014 |
| Pubchem assay | NA |