| Primary information |
|---|
| PRRID | PRRID_1542 |
| Ligand Name | Peptidoglycan (PGN) |
| Source | cell wall of Gram-positive bacteria(Bacteria) |
| Sequence of ligand | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N |
| Length | NA |
| Type | Peptidoglycan |
| Occurence | Natural |
| Role of Ligand | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells |
| Domain | cell surface |
| Sequence of Receptor | Q9QUN7.fasta |
| Swiss prot ID | Q9QUN7 |
| Length Of Receptor | 784 |
| Function | significant role in the pathogenesis of severe inflammatory responses |
| Assay used | Histological analyses, Real-time PCR analysis, Western blotting |
| PMID | 24815695 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1542 |
| Ligand Name | Peptidoglycan (PGN) |
| Source | cell wall of Gram-positive bacteria(Bacteria) |
| Sequence of ligand | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N |
| Length | NA |
| Type | Peptidoglycan |
| Occurence | Natural |
| Role of Ligand | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells |
| Domain | cell surface |
| Sequence of Receptor | Q9QUN7.fasta |
| Swiss prot ID | Q9QUN7 |
| Length Of Receptor | 784 |
| Function | significant role in the pathogenesis of severe inflammatory responses |
| Assay used | Histological analyses, Real-time PCR analysis, Western blotting |
| PMID | 24815695 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |