Primary information |
---|
PRRID | PRRID_1540 |
Ligand Name | Peptidoglycan (PGN) |
Source | Gram-positive bacteria |
Sequence of ligand | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N |
Length | NA |
Type | Peptidoglycan |
Occurence | Natural |
Role of Ligand | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 |
Name of receptor | Toll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells |
Domain | Cell Surface (Exogenous) |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | fundamental role in pathogen recognition and activation of innate immunity. |
Assay used | NA |
PMID | 24830024 |
Year of Publication | 2014 |
Pubchem assay | NA |
Primary information |
---|
PRRID | PRRID_1540 |
Ligand Name | Peptidoglycan (PGN) |
Source | Gram-positive bacteria |
Sequence of ligand | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N |
Length | NA |
Type | Peptidoglycan |
Occurence | Natural |
Role of Ligand | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 |
Name of receptor | Toll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells |
Domain | Cell Surface (Exogenous) |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | fundamental role in pathogen recognition and activation of innate immunity. |
Assay used | NA |
PMID | 24830024 |
Year of Publication | 2014 |
Pubchem assay | NA |