Detailed description page of PRRDB2.0

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PRRID_1532 details
Primary information
PRRIDPRRID_1532
Ligand NamePam3CSK4
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O
LengthNA
TypeLipoprotein
OccurenceSynthetic
Role of Ligandtriacylated lipopeptide potent activator of the proinflammatory transcription factor NF-κB.
Name of receptorToll-like receptor (TLR1/Toll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationmonocyte/macrophages
Domaincell surface
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionplays a fundamental role in pathogen recognition and activation of innate immunity
Assay usedELISA
PMID24771328
Year of Publication2014
Pubchem assayNA
Primary information
PRRIDPRRID_1532
Ligand NamePam3CSK4
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O
LengthNA
TypeLipoprotein
OccurenceSynthetic
Role of Ligandtriacylated lipopeptide potent activator of the proinflammatory transcription factor NF-κB.
Name of receptorToll-like receptor (TLR1/Toll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationmonocyte/macrophages
Domaincell surface
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionplays a fundamental role in pathogen recognition and activation of innate immunity
Assay usedELISA
PMID24771328
Year of Publication2014
Pubchem assayNA