Detailed description page of PRRDB2.0

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PRRID_1529 details
Primary information
PRRIDPRRID_1529
Ligand NamePam3CSK4
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O
LengthNA
TypeLipoprotein
OccurenceSynthetic
Role of Ligandtriacylated lipopeptide potent activator of the proinflammatory transcription factor NF-κB.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
Localizationmonocyte/macrophages
Domaincell surface
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
Functionplays a fundamental role in pathogen recognition and activation of innate immunity
Assay usedELISA
PMID24771854
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1529
Ligand NamePam3CSK4
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O
LengthNA
TypeLipoprotein
OccurenceSynthetic
Role of Ligandtriacylated lipopeptide potent activator of the proinflammatory transcription factor NF-κB.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
Localizationmonocyte/macrophages
Domaincell surface
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
Functionplays a fundamental role in pathogen recognition and activation of innate immunity
Assay usedELISA
PMID24771854
Year of Publication2014
Pubchem assayPubchem_assay