| Primary information |
|---|
| PRRID | PRRID_1527 |
| Ligand Name | Pam3CSK4 |
| Source | Salmonella typhimurium(Bacteria) |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O |
| Length | NA |
| Type | Lipopeptides |
| Occurence | Synthetic |
| Role of Ligand | triacylated lipopeptide potent activator of the proinflammatory transcription factor NF-κB. |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Chicken |
| Localization | splenocytes |
| Domain | cell surface |
| Sequence of Receptor | Q9DD78.fasta |
| Swiss prot ID | Q9DD78 |
| Length Of Receptor | 793 |
| Function | TLR2 and TLR5 promote cellular activation and the production of cytokines including proinflammatory interleukin (IL)-6, as well as those cytokines that help to initiate and modulate the adaptive immune response, including IL-4, IL-12, and interferon (IFN)-c |
| Assay used | ELISA |
| PMID | 24797722 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1527 |
| Ligand Name | Pam3CSK4 |
| Source | Salmonella typhimurium(Bacteria) |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O |
| Length | NA |
| Type | Lipopeptides |
| Occurence | Synthetic |
| Role of Ligand | triacylated lipopeptide potent activator of the proinflammatory transcription factor NF-κB. |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Chicken |
| Localization | splenocytes |
| Domain | cell surface |
| Sequence of Receptor | Q9DD78.fasta |
| Swiss prot ID | Q9DD78 |
| Length Of Receptor | 793 |
| Function | TLR2 and TLR5 promote cellular activation and the production of cytokines including proinflammatory interleukin (IL)-6, as well as those cytokines that help to initiate and modulate the adaptive immune response, including IL-4, IL-12, and interferon (IFN)-c |
| Assay used | ELISA |
| PMID | 24797722 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |