Primary information |
---|
PRRID | PRRID_1519 |
Ligand Name | Paclitaxel |
Source | Pacific yew (plant) |
Sequence of ligand | C1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C |
Length | NA |
Type | Pattern-associated molecular patterns (PAMPs) |
Occurence | Synthetic |
Role of Ligand | used to treat a number of types of cancer |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte |
Domain | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) |
Sequence of Receptor | Q9QUK6.fasta |
Swiss prot ID | Q9QUK6 |
Length Of Receptor | 835 |
Function | plays a fundamental role in pathogen recognition and activation of innate immunity |
Assay used | NA |
PMID | 24754320 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_1519 |
Ligand Name | Paclitaxel |
Source | Pacific yew (plant) |
Sequence of ligand | C1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C |
Length | NA |
Type | Pattern-associated molecular patterns (PAMPs) |
Occurence | Synthetic |
Role of Ligand | used to treat a number of types of cancer |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte |
Domain | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) |
Sequence of Receptor | Q9QUK6.fasta |
Swiss prot ID | Q9QUK6 |
Length Of Receptor | 835 |
Function | plays a fundamental role in pathogen recognition and activation of innate immunity |
Assay used | NA |
PMID | 24754320 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |