Detailed description page of PRRDB2.0

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PRRID_1487 details
Primary information
PRRIDPRRID_1487
Ligand Namemonomeric flagellin
SourceBacteria
Sequence of ligandMAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEGALSEINNNLQRVRELTVQATTGTNSESDLSSIQDEIKSRLDEIDRVSGQTQFNGVNVLAKNGSMKIQVGANDNQTITIDLKQIDAKTLGLDGFSVKNNDTVTTSAPVTAFGATTTNNIKLTGITLSTEAATDTGGTNPASIEGVYTDNGNDYYAKITGGDNDGKYYAVTVANDGTVTMATGATANATVTDANTTKATTITSGGTPVQIDNTAGSATANLGAVSLVKLQDSKGNDTDTYALKDTNGNLYAADVNETTGAVSVKTITYTDSSGAASSPTAVKLGGDDGKTEVVDIDGKTYDSADLNGGNLQTGLTAGGEALTAVANGKTTDPLKALDDAIASVDKFRSSLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQG
Length498
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandIt directly interac with TLR 5 and induces immune response
Name of receptorPGLYRP-2
Type of receptorPeptidoglycan Recognition Receptor (PGRPs)
Source Mice
Localizationmonocyte/macrophages, DCs
DomainCell Surface (Exogenous)
Sequence of ReceptorQ9JLF7.fasta
Swiss prot IDQ9JLF7
Length Of Receptor859
FunctionIt stimulates the production of proinflammatory cytokines, such as TNF-α, through signaling via the adaptor protein MyD88.
Assay usedreverse transcription–polymerase chain reaction (RT–PCR), real-time RT–PCR, flow cytometry, immunocytochemistry and Western blot analysis.
PMID24828022
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1487
Ligand Namemonomeric flagellin
SourceBacteria
Sequence of ligandMAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEGALSEINNNLQRVRELTVQATTGTNSESDLSSIQDEIKSRLDEIDRVSGQTQFNGVNVLAKNGSMKIQVGANDNQTITIDLKQIDAKTLGLDGFSVKNNDTVTTSAPVTAFGATTTNNIKLTGITLSTEAATDTGGTNPASIEGVYTDNGNDYYAKITGGDNDGKYYAVTVANDGTVTMATGATANATVTDANTTKATTITSGGTPVQIDNTAGSATANLGAVSLVKLQDSKGNDTDTYALKDTNGNLYAADVNETTGAVSVKTITYTDSSGAASSPTAVKLGGDDGKTEVVDIDGKTYDSADLNGGNLQTGLTAGGEALTAVANGKTTDPLKALDDAIASVDKFRSSLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQG
Length498
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandIt directly interac with TLR 5 and induces immune response
Name of receptorPGLYRP-2
Type of receptorPeptidoglycan Recognition Receptor (PGRPs)
Source Mice
Localizationmonocyte/macrophages, DCs
DomainCell Surface (Exogenous)
Sequence of ReceptorQ9JLF7.fasta
Swiss prot IDQ9JLF7
Length Of Receptor859
FunctionIt stimulates the production of proinflammatory cytokines, such as TNF-α, through signaling via the adaptor protein MyD88.
Assay usedreverse transcription–polymerase chain reaction (RT–PCR), real-time RT–PCR, flow cytometry, immunocytochemistry and Western blot analysis.
PMID24828022
Year of Publication2014
Pubchem assayPubchem_assay