Detailed description page of PRRDB2.0

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PRRID_1478 details
Primary information
PRRIDPRRID_1478
Ligand NameMALP-2 (macrophage-activating lipopeptide 2)
SourceMycoplasma (Bacteria)
Sequence of ligandC1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)CCC(C(=O)O)N
LengthNA
TypeLipopeptides
OccurenceNatural
Role of LigandIt primes macrophages for cytokines secretion
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source C57BL/6J mice
Localizationmonocyte/macrophages, Myeloid DCs, neutrophils, Mast cells
DomainToll/IL-1R (TIR) domain-containing adaptor molecule MyD88 (myeloid differentiation factor 88)-dependent pathway
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedELISA
PMID24712905
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1478
Ligand NameMALP-2 (macrophage-activating lipopeptide 2)
SourceMycoplasma (Bacteria)
Sequence of ligandC1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)CCC(C(=O)O)N
LengthNA
TypeLipopeptides
OccurenceNatural
Role of LigandIt primes macrophages for cytokines secretion
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source C57BL/6J mice
Localizationmonocyte/macrophages, Myeloid DCs, neutrophils, Mast cells
DomainToll/IL-1R (TIR) domain-containing adaptor molecule MyD88 (myeloid differentiation factor 88)-dependent pathway
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedELISA
PMID24712905
Year of Publication2014
Pubchem assayPubchem_assay