Primary information |
---|
PRRID | PRRID_1478 |
Ligand Name | MALP-2 (macrophage-activating lipopeptide 2) |
Source | Mycoplasma (Bacteria) |
Sequence of ligand | C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)CCC(C(=O)O)N |
Length | NA |
Type | Lipopeptides |
Occurence | Natural |
Role of Ligand | It primes macrophages for cytokines secretion |
Name of receptor | Toll-like receptor 2 (TLR2) |
Type of receptor | Toll-like receptor (TLR) |
Source | C57BL/6J mice |
Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells |
Domain | Toll/IL-1R (TIR) domain-containing adaptor molecule MyD88 (myeloid differentiation factor 88)-dependent pathway |
Sequence of Receptor | Q9QUN7.fasta |
Swiss prot ID | Q9QUN7 |
Length Of Receptor | 784 |
Function | significant role in the pathogenesis of severe inflammatory responses |
Assay used | ELISA |
PMID | 24712905 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_1478 |
Ligand Name | MALP-2 (macrophage-activating lipopeptide 2) |
Source | Mycoplasma (Bacteria) |
Sequence of ligand | C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)CCC(C(=O)O)N |
Length | NA |
Type | Lipopeptides |
Occurence | Natural |
Role of Ligand | It primes macrophages for cytokines secretion |
Name of receptor | Toll-like receptor 2 (TLR2) |
Type of receptor | Toll-like receptor (TLR) |
Source | C57BL/6J mice |
Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells |
Domain | Toll/IL-1R (TIR) domain-containing adaptor molecule MyD88 (myeloid differentiation factor 88)-dependent pathway |
Sequence of Receptor | Q9QUN7.fasta |
Swiss prot ID | Q9QUN7 |
Length Of Receptor | 784 |
Function | significant role in the pathogenesis of severe inflammatory responses |
Assay used | ELISA |
PMID | 24712905 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |