Primary information |
---|
PRRID | PRRID_1462 |
Ligand Name | Loxoribine (7-allyl-7,8-dihydro-8-oxo-guanosine) |
Source | Guanosine (others) |
Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
Length | NA |
Type | Nucleic Acid |
Occurence | Synthetic |
Role of Ligand | up-regulate B-cells lymphoma-2 (Bcl-2) and promote the survival of lung cancer cells |
Name of receptor | Toll-like receptor 7 (TLR7) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | lung cancer cells |
Domain | cell compartment |
Sequence of Receptor | Q9NYK1.fasta |
Swiss prot ID | Q9NYK1 |
Length Of Receptor | 1049 |
Function | important role in the immune response to viral infection |
Assay used | MTT assay, Cell Proliferation Assay |
PMID | 24782650 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_1462 |
Ligand Name | Loxoribine (7-allyl-7,8-dihydro-8-oxo-guanosine) |
Source | Guanosine (others) |
Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
Length | NA |
Type | Nucleic Acid |
Occurence | Synthetic |
Role of Ligand | up-regulate B-cells lymphoma-2 (Bcl-2) and promote the survival of lung cancer cells |
Name of receptor | Toll-like receptor 7 (TLR7) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | lung cancer cells |
Domain | cell compartment |
Sequence of Receptor | Q9NYK1.fasta |
Swiss prot ID | Q9NYK1 |
Length Of Receptor | 1049 |
Function | important role in the immune response to viral infection |
Assay used | MTT assay, Cell Proliferation Assay |
PMID | 24782650 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |