Primary information |
---|
PRRID | PRRID_1460 |
Ligand Name | Loxoribine (7-allyl-7,8-dihydro-8-oxo-guanosine) |
Source | Guanosine (others) |
Sequence of ligand | C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O |
Length | NA |
Type | Pattern-associated molecular patterns (PAMPs) |
Occurence | Synthetic |
Role of Ligand | It activates the innate immune system through Toll-like receptor 7 |
Name of receptor | Toll-like receptor 7 (TLR7) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | monocyte/macrophages, plasmacytoid DCs and B-lymphocytes |
Domain | Cell Compartment/Intracellular (Endosome) |
Sequence of Receptor | P58681.fasta |
Swiss prot ID | P58681 |
Length Of Receptor | 1050 |
Function | important role in the immune response to viral infection |
Assay used | NA |
PMID | 24830024 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_1460 |
Ligand Name | Loxoribine (7-allyl-7,8-dihydro-8-oxo-guanosine) |
Source | Guanosine (others) |
Sequence of ligand | C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O |
Length | NA |
Type | Pattern-associated molecular patterns (PAMPs) |
Occurence | Synthetic |
Role of Ligand | It activates the innate immune system through Toll-like receptor 7 |
Name of receptor | Toll-like receptor 7 (TLR7) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | monocyte/macrophages, plasmacytoid DCs and B-lymphocytes |
Domain | Cell Compartment/Intracellular (Endosome) |
Sequence of Receptor | P58681.fasta |
Swiss prot ID | P58681 |
Length Of Receptor | 1050 |
Function | important role in the immune response to viral infection |
Assay used | NA |
PMID | 24830024 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |