Detailed description page of PRRDB2.0

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PRRID_1429 details
Primary information
PRRIDPRRID_1429
Ligand NameLipopolysaccharide (LPS)
SourceGram negative Bacteria (Bacteria)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
Localizationmonocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte
Domainsignaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF)
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
Functionplays a fundamental role in pathogen recognition and activation of innate immunity
Assay usedNA
PMID24754320
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1429
Ligand NameLipopolysaccharide (LPS)
SourceGram negative Bacteria (Bacteria)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
Localizationmonocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte
Domainsignaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF)
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
Functionplays a fundamental role in pathogen recognition and activation of innate immunity
Assay usedNA
PMID24754320
Year of Publication2014
Pubchem assayPubchem_assay