| Primary information |
|---|
| PRRID | PRRID_1409 |
| Ligand Name | Lipopolysaccharide (LPS) |
| Source | Escherichia coli (0111:B4) (Bacteria) |
| Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
| Length | NA |
| Type | Lipopolysaccharide (LPS) |
| Occurence | Natural |
| Role of Ligand | induce inflammation |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Chicken |
| Localization | monocyte/macrophages |
| Domain | cell surface |
| Sequence of Receptor | Q7ZTG5.fasta |
| Swiss prot ID | Q7ZTG5 |
| Length Of Receptor | 843 |
| Function | TLRs promote cellular activation and the production of cytokines such as interleukin (IL)-12 and interferon (IFN)-c In the case of antigen presenting cells (APCs), TLR stimulation also promotes the up-regulation of major histocompatibility complex class II (MHC-II) and co- stimulatory molecules including CD80 therefore elicitation of a robust adaptive immune response |
| Assay used | ELISA |
| PMID | 24797893 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1409 |
| Ligand Name | Lipopolysaccharide (LPS) |
| Source | Escherichia coli (0111:B4) (Bacteria) |
| Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
| Length | NA |
| Type | Lipopolysaccharide (LPS) |
| Occurence | Natural |
| Role of Ligand | induce inflammation |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Chicken |
| Localization | monocyte/macrophages |
| Domain | cell surface |
| Sequence of Receptor | Q7ZTG5.fasta |
| Swiss prot ID | Q7ZTG5 |
| Length Of Receptor | 843 |
| Function | TLRs promote cellular activation and the production of cytokines such as interleukin (IL)-12 and interferon (IFN)-c In the case of antigen presenting cells (APCs), TLR stimulation also promotes the up-regulation of major histocompatibility complex class II (MHC-II) and co- stimulatory molecules including CD80 therefore elicitation of a robust adaptive immune response |
| Assay used | ELISA |
| PMID | 24797893 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |