| Primary information |
|---|
| PRRID | PRRID_1389 |
| Ligand Name | lipo-arabinomannan |
| Source | Mycobacteria (Bacteria) |
| Sequence of ligand | CCC(CO)NCCNC(CC)CO |
| Length | NA |
| Type | Glycolipid |
| Occurence | Natural |
| Role of Ligand | serve as a modulin with immunoregulatory and anti-inflammatory effects. |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells |
| Domain | extracellular domain with leucine-rich repeats and a conservative intracellular Toll/IL- 1 receptor (TIR) domain |
| Sequence of Receptor | Q9QUN7.fasta |
| Swiss prot ID | Q9QUN7 |
| Length Of Receptor | 784 |
| Function | significant role in the pathogenesis of severe inflammatory responses |
| Assay used | ELISA |
| PMID | 24757287 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1389 |
| Ligand Name | lipo-arabinomannan |
| Source | Mycobacteria (Bacteria) |
| Sequence of ligand | CCC(CO)NCCNC(CC)CO |
| Length | NA |
| Type | Glycolipid |
| Occurence | Natural |
| Role of Ligand | serve as a modulin with immunoregulatory and anti-inflammatory effects. |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells |
| Domain | extracellular domain with leucine-rich repeats and a conservative intracellular Toll/IL- 1 receptor (TIR) domain |
| Sequence of Receptor | Q9QUN7.fasta |
| Swiss prot ID | Q9QUN7 |
| Length Of Receptor | 784 |
| Function | significant role in the pathogenesis of severe inflammatory responses |
| Assay used | ELISA |
| PMID | 24757287 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |