| Primary information |
|---|
| PRRID | PRRID_1387 |
| Ligand Name | L-ornithine muramyl tripeptide |
| Source | Gram-positive bacteria and some Gram-negative spirochaetes. |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCNC(=O)[C@H](C)NC(=O)CC[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@@H]([C@H](O)[C@H](O)CO)[C@@H](NC(=O)C)C=O)C(=O)N)OC(=O)CCCCCCCCCCCCCCC |
| Length | NA |
| Type | Peptide |
| Occurence | Natural |
| Role of Ligand | in vitro activates Nod |
| Name of receptor | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | Human |
| Localization | immune cells like peripheral blood monocytes, granulocytes and dendritic cells, as well as in astrocytes of the brain and in paneth cells of the gut |
| Domain | intracellular receptors |
| Sequence of Receptor | Q9HC29.fasta |
| Swiss prot ID | Q9HC29 |
| Length Of Receptor | 1040 |
| Function | Nod2, are associ- ated with inflammatory bowel disease in humans |
| Assay used | NA |
| PMID | 24779390 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1387 |
| Ligand Name | L-ornithine muramyl tripeptide |
| Source | Gram-positive bacteria and some Gram-negative spirochaetes. |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCNC(=O)[C@H](C)NC(=O)CC[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@@H]([C@H](O)[C@H](O)CO)[C@@H](NC(=O)C)C=O)C(=O)N)OC(=O)CCCCCCCCCCCCCCC |
| Length | NA |
| Type | Peptide |
| Occurence | Natural |
| Role of Ligand | in vitro activates Nod |
| Name of receptor | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | Human |
| Localization | immune cells like peripheral blood monocytes, granulocytes and dendritic cells, as well as in astrocytes of the brain and in paneth cells of the gut |
| Domain | intracellular receptors |
| Sequence of Receptor | Q9HC29.fasta |
| Swiss prot ID | Q9HC29 |
| Length Of Receptor | 1040 |
| Function | Nod2, are associ- ated with inflammatory bowel disease in humans |
| Assay used | NA |
| PMID | 24779390 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |