Primary information |
---|
PRRID | PRRID_1382 |
Ligand Name | internalized flagellin |
Source | Salmonella typhimurium or Legionella pneumophila (Bacteria) |
Sequence of ligand | KLSFEDKNGKVIDGGYAVKMGDDFYAATYDEKTGAITAKTTTYTDGTGVAQTGAVKFGGANGKSEVVTATDGKTYL |
Length | 76 |
Type | Protein |
Occurence | Natural |
Role of Ligand | Flagellin and LPS stimulate the production of CXCL1 and CXCL2 |
Name of receptor | Nod-like receptor C4 (NLRC4) |
Type of receptor | NOD-like receptor (NLR) |
Source | Human |
Localization | medullary collecting duct (MCD) cells |
Domain | intracellular receptors |
Sequence of Receptor | Q9NPP4.fasta |
Swiss prot ID | Q9NPP4 |
Length Of Receptor | 1024 |
Function | assemble in an inflammasome complex to activate caspase-1 and promote the release of IL-1β and IL-18 |
Assay used | ELISA, adhesion and invasion assay |
PMID | 24779433 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_1382 |
Ligand Name | internalized flagellin |
Source | Salmonella typhimurium or Legionella pneumophila (Bacteria) |
Sequence of ligand | KLSFEDKNGKVIDGGYAVKMGDDFYAATYDEKTGAITAKTTTYTDGTGVAQTGAVKFGGANGKSEVVTATDGKTYL |
Length | 76 |
Type | Protein |
Occurence | Natural |
Role of Ligand | Flagellin and LPS stimulate the production of CXCL1 and CXCL2 |
Name of receptor | Nod-like receptor C4 (NLRC4) |
Type of receptor | NOD-like receptor (NLR) |
Source | Human |
Localization | medullary collecting duct (MCD) cells |
Domain | intracellular receptors |
Sequence of Receptor | Q9NPP4.fasta |
Swiss prot ID | Q9NPP4 |
Length Of Receptor | 1024 |
Function | assemble in an inflammasome complex to activate caspase-1 and promote the release of IL-1β and IL-18 |
Assay used | ELISA, adhesion and invasion assay |
PMID | 24779433 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |