Detailed description page of PRRDB2.0

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PRRID_1380 details
Primary information
PRRIDPRRID_1380
Ligand NameIMO-2055
SourceNA
Sequence of ligandNA
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandit enhances the efficacy of antitumor agents through immune stimulation
Name of receptorToll-like receptor 9 (TLR9)
Type of receptorToll-like receptor (TLR)
Source Human patients with advanced non-small cell lung cancer (nSClC)
Localizationmonocyte/macrophages, plasmacytoid DCs and B-lymphocytes
Domaincell compartment
Sequence of ReceptorQ9NR96.fasta
Swiss prot IDQ9NR96
Length Of Receptor1032
FunctionTLR9 plays a crucial role in breaking tolerance and developing autoimmunity
Assay usedNA
PMID24770667
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1380
Ligand NameIMO-2055
SourceNA
Sequence of ligandNA
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandit enhances the efficacy of antitumor agents through immune stimulation
Name of receptorToll-like receptor 9 (TLR9)
Type of receptorToll-like receptor (TLR)
Source Human patients with advanced non-small cell lung cancer (nSClC)
Localizationmonocyte/macrophages, plasmacytoid DCs and B-lymphocytes
Domaincell compartment
Sequence of ReceptorQ9NR96.fasta
Swiss prot IDQ9NR96
Length Of Receptor1032
FunctionTLR9 plays a crucial role in breaking tolerance and developing autoimmunity
Assay usedNA
PMID24770667
Year of Publication2014
Pubchem assayPubchem_assay