Detailed description page of PRRDB2.0

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PRRID_1373 details
Primary information
PRRIDPRRID_1373
Ligand NameImiquimod
SourceNA
Sequence of ligandCC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceSynthetic
Role of LigandAmine analog to guanosine, is an immune response modifier with potent indirect antiviral activity.
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationSpleen cells
Domaincell compartment
Sequence of ReceptorQ9NYK1.fasta
Swiss prot IDQ9NYK1
Length Of Receptor1049
Functionimportant role in the immune response to viral infection
Assay usedwhole blood assay (WBA), ELISA
PMID24766820
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1373
Ligand NameImiquimod
SourceNA
Sequence of ligandCC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceSynthetic
Role of LigandAmine analog to guanosine, is an immune response modifier with potent indirect antiviral activity.
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationSpleen cells
Domaincell compartment
Sequence of ReceptorQ9NYK1.fasta
Swiss prot IDQ9NYK1
Length Of Receptor1049
Functionimportant role in the immune response to viral infection
Assay usedwhole blood assay (WBA), ELISA
PMID24766820
Year of Publication2014
Pubchem assayPubchem_assay