Detailed description page of PRRDB2.0

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PRRID_1332 details
Primary information
PRRIDPRRID_1332
Ligand NameHMGB1
SourceEndogenous (others)
Sequence of ligandMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE
Length215
TypeProtein
OccurenceNatural
Role of Ligandplay an important role in infectious inflammatory responses.
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
Localization(DCs)Dendritic cells
Domaincell surface
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionTLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system
Assay usedNA
PMID24825061
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1332
Ligand NameHMGB1
SourceEndogenous (others)
Sequence of ligandMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE
Length215
TypeProtein
OccurenceNatural
Role of Ligandplay an important role in infectious inflammatory responses.
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
Localization(DCs)Dendritic cells
Domaincell surface
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionTLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system
Assay usedNA
PMID24825061
Year of Publication2014
Pubchem assayPubchem_assay