Detailed description page of PRRDB2.0

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PRRID_1300 details
Primary information
PRRIDPRRID_1300
Ligand NameFSL-1
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCCCC(=O)OCC(CSC[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCCN)C(=ON[C@@H(COC(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)N)OC(=O)CCCCCCCCCCCCCCC
LengthNA
TypeLipoprotein
OccurenceSynthetic
Role of Ligandmimic parts of bacterial lipoproteins
Name of receptorToll-like receptor 2/6 (TLR2/6)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationmast cells
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionfundamental role in pathogen recognition and activation of innate immunity.
Assay usedReal-time PCR
PMID24736205
Year of Publication2014
Pubchem assayNA
Primary information
PRRIDPRRID_1300
Ligand NameFSL-1
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCCCC(=O)OCC(CSC[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCCN)C(=ON[C@@H(COC(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)N)OC(=O)CCCCCCCCCCCCCCC
LengthNA
TypeLipoprotein
OccurenceSynthetic
Role of Ligandmimic parts of bacterial lipoproteins
Name of receptorToll-like receptor 2/6 (TLR2/6)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationmast cells
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionfundamental role in pathogen recognition and activation of innate immunity.
Assay usedReal-time PCR
PMID24736205
Year of Publication2014
Pubchem assayNA