| Primary information |
|---|
| PRRID | PRRID_1261 |
| Ligand Name | Endogenous DNA from dead cells |
| Source | Mice (others) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | EV71 induces cellular apoptosis, resulting in tissue damage; the endogenous DNA from dead cells activate the innate immune system through TLR9. |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Dendritic cells |
| Domain | LRR |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | This leads to the antiviral response against EV71 |
| Assay used | Cytokines assay |
| PMID | 25078697 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1261 |
| Ligand Name | Endogenous DNA from dead cells |
| Source | Mice (others) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | EV71 induces cellular apoptosis, resulting in tissue damage; the endogenous DNA from dead cells activate the innate immune system through TLR9. |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Dendritic cells |
| Domain | LRR |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | This leads to the antiviral response against EV71 |
| Assay used | Cytokines assay |
| PMID | 25078697 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |